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Amazon Best Sellers
Our most popular products based on sales. Updated frequently.
Best Sellers in Pain Relief Medications & Treatments
#1
Amazon Basic Care Ibuprofen Tablets 200 mg, Pain Reliever/Fever Reducer, Body Aches, Headache, Arthritis Pain Relief and More, 500 Count
4.8 out of 5 stars
71,520
1 offer from
$9.16
#2
Tylenol Extra Strength Acetaminophen Rapid Release Gels, Pain Reliever & Fever Reducer, 100 ct
4.8 out of 5 stars
63,968
34 offers from
$11.00
#3
Tylenol Extra Strength Caplets with 500 mg Acetaminophen, Pain Reliever & Fever Reducer, 100 ct
4.8 out of 5 stars
42,596
21 offers from
$9.90
#4
TUCKS Medicated Cooling Pads, 100 Count – Pads with Witch Hazel, Cleanses Sensitive Areas, Protects from Irritation, Hemorrhoid Treatment, Medicated Pads Used By Hospitals
4.8 out of 5 stars
52,076
52 offers from
$7.68
#5
Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, 200 Count
4.8 out of 5 stars
66,582
1 offer from
$4.78
#6
Boiron Arnicare Gel for Soothing Relief of Joint Pain, Muscle Pain, Muscle Soreness, and Swelling from Bruises or Injury - Non-greasy and Fragrance-Free - 2.6 oz
4.6 out of 5 stars
48,286
19 offers from
$8.32
#7
Bayer Aspirin Low Dose 81 mg, Enteric Coated Tablets, Doctor Recommended, Secondary Prevention of Cardiovascular Disease, 300 Safety Coated Tablets
4.9 out of 5 stars
28,414
2 offers from
$10.73
#8
Penetrex Joint & Muscle Therapy – Soothing Comfort for Back, Neck, Hands, Feet – Premium Whole Body Rub with Arnica, Vitamin B6 MSM & Boswellia – Non-Greasy 2oz Cream
4.2 out of 5 stars
80,257
4 offers from
$14.21
#9
Preparation H Hemorrhoid Symptom Treatment Cream (0.9 Ounce Tube), Maximum Strength Multi-Symptom Pain Relief with Aloe
4.6 out of 5 stars
34,798
18 offers from
$7.28
#10
TheraICE Migraine Relief Cap, Soothing Headache Ice Pack Mask Products, Cooling Gel Hat, Face Cold Compress Head Wrap for Tension, Stress & Hangover
4.6 out of 5 stars
36,482
1 offer from
$29.95
#11
Tylenol Infants' Liquid Medicine with Acetaminophen Pain + Fever Relief DyeFree fl, Red, Cherry, 2 Fl Oz
4.9 out of 5 stars
23,791
37 offers from
$9.75
#12
Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief - NEW Easy Open Cap - 100 g x 2
4.5 out of 5 stars
53,163
5 offers from
$32.95
#13
GENIANI King Size Heating Pad for Back Pain & Cramps Relief, FSA HSA Eligible, Auto Shut Off, Machine Washable, Moist Heat Pad for Neck & Shoulder, Knee, Leg, Heat Patches, Tabby Gray 12'‘×24’’
4.3 out of 5 stars
55,670
1 offer from
$35.97
#14
Salonpas Pain Relieving Patch for Back, Neck, Shoulder, Knee Pain and Muscle Soreness - 8 Hour Pain Relief - 60 Count
4.6 out of 5 stars
30,903
38 offers from
$9.99
#15
Tylenol 8 Hour Arthritis Pain Tablets with Acetaminophen for Joint Pain, 100 ct
4.8 out of 5 stars
31,988
22 offers from
$11.45
#16
FlexiKold Large Gel Soft Flexible Ice Packs for Injuries Reusable – Cooling Pad Ice Wrap for Injuries, Back Pain, Migraine Relief, Surgery Recovery, Headache, Shoulder – Standard – 10.5” x 14.5”
4.7 out of 5 stars
54,985
1 offer from
$19.99
#17
Advil Pain Reliever and Fever Reducer, Medicine with Ibuprofen 200mg for Headache, Backache, Menstrual and Joint Pain Relief - 50x2 Coated Tablets
4.9 out of 5 stars
17,632
28 offers from
$9.99
#18
Advil Pain Reliever Medicine and Fever Reducer with Ibuprofen 200mg for Headache, Backache, Menstrual Pain and Joint Pain Relief - 300 Coated Tablets
4.9 out of 5 stars
12,437
22 offers from
$11.66
#19
AZO Urinary Pain Relief Maximum Strength | Fast relief of UTI Pain, Burning & Urgency | Targets Source of Pain | #1 Most Trusted Brand | 24 Tablets
4.7 out of 5 stars
31,955
19 offers from
$7.98
#20
Hyland's Naturals Leg Cramp Tablets, Natural Relief of Calf, Leg and Foot Cramp, Quick Dissolving Tablets, 100 Count
4.5 out of 5 stars
17,004
12 offers from
$12.00
#21
OmegaXL Joint Support Supplement, for Relief - Natural Muscle Support, Green Lipped Mussel Oil, Soft Gel Pills, Drug-Free, 60 Count
4.2 out of 5 stars
29,639
27 offers from
$41.25
#22
Heating Pad for Neck and Shoulder, Gifts for Men Women Mom Dad, Weighted Neck Heating Pad for Neck Pain Relief, Birthday Anniversary Retirement Mothers Day Gifts, Blue
4.5 out of 5 stars
512
2 offers from
$39.99
#23
Tylenol PM Extra Strength Nighttime Pain Reliever & Sleep Aid Caplets, 500 mg Acetaminophen & 25 mg Diphenhydramine HCl, Relief for Nighttime Aches & Pains, Non-Habit Forming, 100 ct
4.8 out of 5 stars
20,509
15 offers from
$13.32
#24
Preparation H Hemorrhoid Flushable Wipes with Witch Hazel for Skin Irritation Relief - 48 Count
4.7 out of 5 stars
4,419
10 offers from
$5.92
#25
Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief - NEW Easy Open Cap - 150 g
4.5 out of 5 stars
7,612
18 offers from
$19.50
#26
Heating Pad for Back Pain Relief & Cramps, KOT Heating Pads with Auto Shut Off Large, 6 Heat Settings Electric Heated Pad, Gifts for Women, Gifts for Men, 12" x 24"
4.6 out of 5 stars
2,971
3 offers from
$23.97
#27
Bruder Moist Heat Eye Compress | Microwave Activated | Fast Acting and Effective Relief for Dry Eye and Other Eye Irritation
4.5 out of 5 stars
24,716
11 offers from
$20.95
#28
D-Mannose 1,300 mg with Cranberry Extract Fast-Acting, Flush Impurities, Natural Urinary Tract Health- 100 Veggie Capsules
4.7 out of 5 stars
13,859
3 offers from
$17.88
#29
Motrin IB, Ibuprofen 200mg Tablets for Fever, Muscle Aches, Headache & Backache, 225 Ct
4.8 out of 5 stars
15,070
12 offers from
$12.65
#30
Tylenol Extra Strength Dissolve Packs, 500 mg Acetaminophen Pain Reliever & Fever Reducer, On-The-Go Powder Packets for Minor Aches & Pains, Ibuprofen- & Aspirin-Free, Berry Flavor, 32 ct
4.8 out of 5 stars
12,952
29 offers from
$12.69
#31
Doctor Butler’s Hemorrhoid & Fissure Ointment Cream with Lidocaine and Phenylephrine HCI for Fast Acting Relief of Pain, Swelling, Discomfort, and Itching (1 oz.)
4.3 out of 5 stars
22,966
1 offer from
$29.95
#32
Ebanel 5% Lidocaine Numbing Cream, Pain Relief Cream Burn Itch Cream, Numb520 Topical Anesthetic Lidocaine Cream Maximum Strength with Vitamin E for Local and Anorectal Uses, Hemorrhoid Treatment
4.1 out of 5 stars
73,543
2 offers from
$17.69
#33
Heating Pad for Neck and Shoulders, NIUONSIX Mothers Day Gifts, 2lb Weighted Neck Heating Pad for Pain Relief 6 Heat Settings 4 Timers Auto Off, Gifts for Women Mom Men Dad Birthday Anniversary, Blue
4.5 out of 5 stars
6,407
5 offers from
$31.87
#34
Advil Liqui-Gels minis Pain Reliever and Fever Reducer, Pain Medicine for Adults with Ibuprofen 200mg for Pain Relief - 200 Liquid Filled Capsules
4.9 out of 5 stars
15,819
10 offers from
$19.47
#35
Amazon Basic Care Aspirin 81 mg Pain Reliever (NSAID) Chewable Tablets, Low Dose , Orange Flavor, 108 Count (3 Packs of 36)
4.8 out of 5 stars
11,123
1 offer from
$5.98
#36
HealthCareAisle Diclofenac Gel, 1%, Arthritis Pain Relief - 150 g tube - Original Prescription Strength (NSAID)
4.5 out of 5 stars
10,426
2 offers from
$12.59
#37
Salonpas Pain Relieving Patch, LARGE, 6 Count, for Back, Neck, Shoulder, Knee Pain and Muscle Soreness, 8 Hour Pain Relief
4.6 out of 5 stars
13,453
26 offers from
$5.23
#38
Tylenol Children's Oral Suspension Medicine with Acetaminophen, Cherry, 4 Fl Oz
4.8 out of 5 stars
15,733
41 offers from
$7.65
#39
Tylenol 8 Hour Arthritis Pain Relief Extended-Release Tablets, 650 mg Acetaminophen, Joint Pain Reliever & Fever Reducer Medicine, Oral Pain Reliever for Arthritis & Joint Pain, 225 Count
4.8 out of 5 stars
2,334
27 offers from
$18.93
#40
Preparation H Hemorrhoid Ointment, Itching, Burning and Discomfort Relief - 1 Oz Tube
4.6 out of 5 stars
12,356
15 offers from
$2.99
#41
Rite Aid Extra Strength 500 mg Acetaminophen Pain Relief, Rapid Release Gelcaps - 225 Count | Pain Reliever, Joint Pain Relief | Muscle Pain Relief | Arthritis Pain Relief | Back Pain Relief Products
4.8 out of 5 stars
10,118
5 offers from
$14.95
#42
Excedrin Migraine Relief Caplets to Alleviate Migraine Symptoms - 200 Count
4.9 out of 5 stars
9,132
7 offers from
$18.50
#43
Heating Pad for Neck and Shoulders and Back, Comfytemp Mothers Day Gifts, FSA HSA Eligible Weighted Electric Heat Pad for Pain Relief, 2.6lb Large Heated Wrap, Birthday Gifts for Women Men Mom Dad
4.3 out of 5 stars
17,313
3 offers from
$33.78
#44
Midol Complete Menstrual Pain Relief Caplets, 40 Count - Provides Cramp, Headache, and Bloating Relief
4.8 out of 5 stars
16,099
9 offers from
$7.37
#45
Amazon Basic Care Children’s Ibuprofen Chewable Tablets, 100 mg, Orange Flavor, Pain Reliever and Fever Reducer, For Minor Aches and Pains, Sore Throat, Headache Relief and More, 24 Count
4.8 out of 5 stars
6,735
1 offer from
$5.49
#46
Bengay Ultra Strength Topical Pain Relief Cream, Non-Greasy Topical Analgesic for Minor Arthritis, Muscle, Joint, and Back Pain, Camphor, Menthol & Methyl Salicylate, 4 oz
4.7 out of 5 stars
14,514
39 offers from
$5.58
#47
Heating Pad-Electric Heating Pads for Back,Neck,Abdomen,Moist Heated Pad for Shoulder,Knee,Hot Pad for Arms and Legs,Dry&Moist Heat & Auto Shut Off,Mothers Day Gifts for Mom(Light Gray, 12''×24')
4.3 out of 5 stars
171
2 offers from
$13.79
#48
Tylenol Extra Strength Acetaminophen Rapid Release Gels, Pain Reliever & Fever Reducer Medicine, Gelcaps with Laser-Drilled Holes, 500 mg Acetaminophen, 225 ct(Packaging May Vary)
4.9 out of 5 stars
5,062
20 offers from
$18.00
#49
Boiron Arnicare Bruise Cream for Pain Relief from Bruising and Swelling or Discoloration from Injury - 1.4 oz(Pack of 1)
4.5 out of 5 stars
2,470
7 offers from
$8.49
#50
A+Health Ibuprofen 200 Mg Softgels, Pain Reliever/Fever Reducer (NSAID), Made in USA, 300 Count
4.7 out of 5 stars
12,553
1 offer from
$12.63
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