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Nucific® Bio-X4 4-in-1 Weight Management Probiotic Supplement, 90 Count.

3.8 3.8 out of 5 stars 9,632 ratings
$53.10 with 10 percent savings $0.59 per Count
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-15% $50.15 ($0.56 / Count)
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Purchase options and add-ons

Brand Nucific
Unit Count 90 Count
Item Form Capsule
Item Weight 0.4 Pounds
Product Benefits Metabolism Management, Weight Loss Support, Digestive Health Support
Age Range (Description) Adult
Package Information Bottle
Number of Items 1
Servings per Container 90
Dosage Form Capsule

About this item

  • BIO-X4 is our 4-in-1 weight management probiotic that works to optimize your digestive system from the inside out. Each capsule is packed with 4 nutrients to help balance your digestive system, supercharge your metabolism, curb your unhealthy cravings, and support your weight loss efforts. It’s like getting 4 powerful formulas in 1 — which work together to help you look AND feel fantastic.*
  • BIO-X4 takes a multi-pronged approach to digestive health. Every capsule of BIO-X4 is packed with powerful, science-backed ingredients to help balance your digestive system, supercharge your metabolism, curb your unhealthy cravings, and help you achieve weight loss results that have eluded you for years.*
  • For optimal results, take 1 capsule with each meal, 3 times per day. You can take up to 2 capsules per meal, but do not exceed 6 capsules a day. If you accidentally miss a serving, or even an entire day, just continue as normal the next day.
  • Please note, BIO-X4 contains a Manufacture Date, this is NOT an expiration date. The potency validation of BIO-X4 is 1 year from Date of Manufacture.

Additional Details

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Product Description

bio x 4 better quality
bio x 4 faq better quality
brand statement better quality

Product details

  • Package Dimensions ‏ : ‎ 5.04 x 2.72 x 2.52 inches; 6.38 ounces
  • Date First Available ‏ : ‎ August 16, 2019
  • Manufacturer ‏ : ‎ Joliano
  • ASIN ‏ : ‎ B07WH3Y5L7
  • Customer Reviews:
    3.8 3.8 out of 5 stars 9,632 ratings

Important information

Legal Disclaimer

Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

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Customer reviews

3.8 out of 5 stars
3.8 out of 5
9,632 global ratings

Customers say

Customers like the quality of the product, saying it's an excellent, high quality product. They also say it'll work for them and is amazing. However, some customers have reported issues with performance, value, and comfort. They say it didn't work for their needs, was overpriced, and gave them uncomfortable intestinal issues. Customers also are disappointed with the bottle quality. Opinions are mixed on digestion.

AI-generated from the text of customer reviews

162 customers mention85 positive77 negative

Customers are mixed about the digestion of the nutritional supplement. Some mention that it stops cravings and decreases their appetite, helping them control hunger and promote healthy eating habits. They also say it has a good effect on bowel activities. However, others say that it causes horrific stomach issues, bloating, and pain.

"I like everything about this product: the easy weight loss, the way it does not let fat settle in my stomach, the constant steady weight loss which..." Read more

"So over rated. Does not help control appetite." Read more

"...I believe this product has helped me not desire sugar or cravings for snacks...." Read more

"...I attempted to take the product for 2-weeks and it caused a lot stomach ache and pain...." Read more

41 customers mention28 positive13 negative

Customers like the quality of the nutritional supplement. They say it's an excellent product, worth a try, and high quality. Some customers also mention that it has been amazing for gut health and is convincing. Overall, most are happy with the convenience of all the enzymes and probiotics in one capsule.

"This product is good. When I received item I place in the pantry. When I went back to open for use the bottle is broken. This item is expensive $60...." Read more

"Great product" Read more

"Absolutely no discernable changes after taking for 29 days, on day 30 I developed a skin rash...." Read more

"The item is a decent probiotic, but it doesn’t stand up to the other claims of appetite suppression and promotion of weight loss...." Read more

98 customers mention24 positive74 negative

Customers are dissatisfied with the performance of the nutritional supplement. They mention that it didn't work for them, didn''t make any difference, and failed the test. Some say that the product is not efficient and does not agree with their system.

"...I cannot praise it's benefits or disclaim it's promises. For me it was not efficient. Therefore I cannot recommend nor disparage it." Read more

"This did not work as it says, I will never buy it again. Very unhappy customer." Read more

"Ordered on Amazon. No measurable impact after 2 weeks. 90 day Money back guarantee is only good if you buy direct from manufacture...." Read more

"It works perfectly" Read more

72 customers mention5 positive67 negative

Customers are not satisfied with the value of the nutritional supplement. They mention that it's not worth the money, overpriced, and a waste of money. Some customers also say that the product is out dated and unacceptable.

"...I’m not sure if they really worked. They were very expensive so I think I’m gonna try a different brand." Read more

"It is pretty expensive. $57 for a months supply. The ads say it will take a month to see results, glass bottle to keep the quality high" Read more

"...did not feel anything but it Did make my skin itch, cannot use, plus overpriced vs. the competition." Read more

"...But her pricing is a scam. She charged $31 on Amazon, then $99 on her website, and then she raised her Amazon price to $50...." Read more

47 customers mention9 positive38 negative

Customers are not happy with the comfort of the nutritional supplement. They mention that it gives them very uncomfortable intestinal issues, makes their stomach hurt, and constipates them. Some customers also experience headaches, dizziness, and diarrhea.

"Used for 30 days and did not feel anything but it Did make my skin itch, cannot use, plus overpriced vs. the competition." Read more

"...At night it's the worst because laying down makes the nausea worse. So a few restless nights.The only positive is I stopped snacking...." Read more

"Used this a few years ago and it was wonderful. Upset my stomach terribly this time around and you can’t return it!" Read more

"...After one week of use, I was noticing some stomach pains and a significant reduction of my regularity. I subsequently put the bottle on the shelf." Read more

18 customers mention0 positive18 negative

Customers are dissatisfied with the bottle quality of the nutritional supplement. They mention that the bottle arrived broken, cracked, and damaged. Some say that the container or cap is damaged. They also say that pills were everywhere when they opened the package. Some customers also say the bottle appears tampered with and has no expiration date.

"...When I went back to open for use the bottle is broken. This item is expensive $60. I need my money back.Thank you for your time." Read more

"...Glass bottle shipped in a plastic envelope and arrived damaged. Very disappointed. Breakable and crushable items should be shipped in a box!!" Read more

"...] I just received them and the glass bottle is broken pills were everywhere when I opened the package about the pills I’m yet to use them and see..." Read more

"Plan to start my diet Feb 1st. I just opened package. Bottle was not sealed and only 87 capsules in, not 90." Read more

Item bottle arrived broken.
4 Stars
Item bottle arrived broken.
This product is good. When I received item I place in the pantry. When I went back to open for use the bottle is broken. This item is expensive $60. I need my money back.Thank you for your time.
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Top reviews from the United States

Christine Sheppard
5.0 out of 5 stars Lost 20 lbs since October
Reviewed in the United States on November 18, 2023
Verified Purchase
I like everything about this product: the easy weight loss, the way it does not let fat settle in my stomach, the constant steady weight loss which is encouraging, the ability to be more selective in what I eat which eliminates consuming too many sweets. Food now is not my overwhelming priority. No side effects. I love this product. I hope it works the same through the excess weight loss of which I must rid myself. Plus, this product is healthy even if I were not to take it for weight loss.
62 people found this helpful
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Mr Styles Romero
5.0 out of 5 stars Nucific BIO-X4 Who could ask for anything more?
Reviewed in the United States on September 13, 2022
Verified Purchase
First, I love the product just after a week of receiving my product. The product does exactly what it states. There is no mystery to those of us that know the importance of "gut health". I am not new to proper nutrition and gut health. I was seeking exactly this product. A product balanced with Amylase, Lipase, and Bromelain and the prebiotic and probiotic.

To the naysayers, here is some advice that goes with almost any product you purchase in the United States. Always consult your Doctor/Physician before starting any new supplement, especially if you have medical conditions. See how easy life can be?

Next, there is No Miracle in a bottle, bag, box, or any other receptacle. There is cheating with your weight loss and get fit regimen, but we all know the payoff. Do you like your easy weekends and consuming alcohol/beer? Do you enjoy cheese, dairy, ice cream, pizza, salty foods, fried foods, sugar snacks, and chips? You cannot get away from them bad grains, dairy, condiments, and a host of other products you should have researched before seeking the genie in a bottle.

Have a healthy understanding of this product and any other product you decide to commit to after you have consulted with your doctor or physician. You should learn more about your gut health and proper nutrition. 90% of your body's living and thriving is based on your gut health and then your organs. You should try to develop a regular regimen of drinking water because sugar and chemicals are your enemies. Learn more about your "stomach lining." Once you have put all these factors into play maybe have a conversation in your mirror. Tell yourself the truth. Ask yourself if you're ready to change your health by eating right, drinking right, sleeping right, and getting the proper water daily.

There is no miracle fix-it-overnight pill or liquid or powder. However, I firmly stand behind Nucific products and will continue to use them for optimal gut health.

Good Luck on Your Healthy Gut Journey!
502 people found this helpful
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Bruce Alan Mcknight
1.0 out of 5 stars Had no impact on my digestive health
Reviewed in the United States on December 8, 2021
Verified Purchase
This is a tough one to write. I'm almost to the end of my first bottle. I have seen no effect one way or the other on my digestive health. It could be that I already lead a fairly healthy lifestyle. I watch what I eat most of the time. It's not a totally clean nutrition plan but I do opt for carrot sticks over chips for TV snacking. I also keep a food log. I don't use it to track my nutrition from day to day or limit serving sizes. It's more to keep me mindful of the overall calories. I consume very little caffeine and don't consume alcohol except for a beer or a glass of wine once in a while (2-3 times a month).

I never experienced the intestinal discomfort others mentioned. There hasn't been a change in regularity or amount of output. The level of gas emission hasn't changed, nor has there been any change in "fragrance". I also haven't felt any appetite suppression. There has been no change in my blood pressure or my blood sugar level. Diabetes runs in my family so I measure my glucose first thing every Monday morning. It has been 80-85 for the past several years.

I'm actually happy not to have the same impacts others have reported but from my experience, the capsules I received could be completely inert.

So this isn't a negative review of the product. It's more of a "It did nothing for or to me. Your results may differ" kind of review.
276 people found this helpful
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AMLENTZ
3.0 out of 5 stars It's difficult to quantify the results.
Reviewed in the United States on October 6, 2023
Verified Purchase
I took as prescribed and did not discover their claims of benefit. It looks like a plain capsule with brown powder. I cannot praise it's benefits or disclaim it's promises. For me it was not efficient. Therefore I cannot recommend nor disparage it.
92 people found this helpful
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E. Thomas
4.0 out of 5 stars Item bottle arrived broken.
Reviewed in the United States on January 6, 2024
Verified Purchase
This product is good. When I received item I place in the pantry. When I went back to open for use the bottle is broken. This item is expensive $60. I need my money back.
Thank you for your time.
Customer image
E. Thomas
4.0 out of 5 stars Item bottle arrived broken.
Reviewed in the United States on January 6, 2024
This product is good. When I received item I place in the pantry. When I went back to open for use the bottle is broken. This item is expensive $60. I need my money back.
Thank you for your time.
Images in this review
Customer image
Customer image
19 people found this helpful
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Eddy Mwelwa
5.0 out of 5 stars Item is not fake
Reviewed in the United States on April 30, 2024
Verified Purchase
Food supplement for weight management
One person found this helpful
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Raj
2.0 out of 5 stars Save your $
Reviewed in the United States on April 29, 2024
Verified Purchase
So over rated. Does not help control appetite.
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