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Jarrow Formulas SAMe 200 mg - 20 Tablets - Highest Concentration of Active S,S Form - Supports Joint Health, Liver Function, Brain Metabolism & Antioxidant Defense - 20 Servings
Purchase options and add-ons
Brand | Jarrow Formulas |
Flavor | Unflavored |
Unit Count | 20 Count |
Item Form | Tablet,Tablets |
Item Weight | 0.08 Pounds |
Item Dimensions LxWxH | 2 x 3 x 5 inches |
Diet Type | Vegetarian, Vegan |
Product Benefits | Mood Support |
Age Range (Description) | Adult |
Number of Items | 1 |
About this item
- to: Highest Concentration of Active S,S Form - The S,S structure is the biologically active form of SAMe. The formula is made naturally by fermentation & processed without chemical solvents to preserve 68-80% S,S SAMe.
- to: Joint Health, Liver Function & Antioxidant Defense - SAMe supports the production of healthy connective tissue.* Plus, SAMe metabolism supports the synthesis of glutathione, which is critical for antioxidant defenses and liver functions.*
- Brain Metabolism - SAMe methylation reactions are involved in the synthesis of phosphatidylcholine and neurotransmitters such as dopamine, norepinephrine, and serotonin.*
- to: Enteric Coating - SAMe provides 200 mg SAMe (net yield) from 400 mg of SAMe tosylate disulfate. It is manufactured under low temperature and low humidity, and enteric-coated to ensure a biologically active product.*
- to: Superior Science, Smarter Formulas - Informed by strong scientific research, Jarrow Formulas products are carefully crafted to ensure you get the benefit of each and every vitamin, mineral and supplement.
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From the manufacturer
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Our formulations are carefully crafted and informed by strong scientific research. We are 100% dedicated to getting every formula right. |
Our mental wellness supplements include ingredients such as Magtein, Cognizin Citicoline and Sharp-PS that support brain health, certain aspects of cognition, positive mood, and deep sleep.* |
We evaluate ingredient purity and only work with suppliers who follow Current Good Manufacturing Practices (cGMP) for our capsules, tablets, softgels and powder formulations. |
MagMind Brain Health | Theanine 200 | SAMe 400 | Neuro Optimizer | Ashwagandha | Alpha GPC | |
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Customer Reviews |
4.6 out of 5 stars
4,023
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4.5 out of 5 stars
2,286
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4.4 out of 5 stars
592
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4.5 out of 5 stars
1,023
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4.5 out of 5 stars
1,781
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4.5 out of 5 stars
527
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Primary Benefit | Supports Brain Health, Function & Memory^* ^In healthy adults | Promotes Relaxation* | Supports Balanced Mood, Joint Health & Liver Function* | Supports Neuron & Normal Stress Response* | Supports Normalized Resistance to Mental & Physical Stress* | Support Brain Function* |
Key Ingredients | Magtein Magnesium | L-Theanine | S-Adenosyl Methionine | Cognizin Citicoline, Sharp-PS Phosphatidylserine | Ashwagandha Extract | Alpha GPC |
No Major Allergens | ✓ | ✓ | ✓ | ✓ | ||
Form Type | Veggie Capsule | Veggie Capsule | Tablet | Capsule | Veggie Capsule | Veggie Capsule |
Size Options | 90 | 60 | 30 & 60 | 120 | 120 | 60 |
Product Description
We use superior science to make smarter formulas like Jarrow Formulas� SAMe 200, a metabolite of methionine (an essential amino acid). It provides a full 200 mg SAMe (net yield) from 400 mg of SAMe tosylate disulfate. The S,S structure is the biologically active form of SAMe. This formula is made naturally by fermentation and processed without chemical solvents to preserve 68-80% S,S SAMe. SAMe supports the production of healthy connective tissue.* Plus, SAMe metabolism supports the synthesis of glutathione, which is critical for antioxidant defenses and liver functions.* SAMe methylation reactions are involved in the synthesis of phosphatidylcholine and neurotransmitters such as dopamine, norepinephrine, and serotonin.* The formula is manufactured under low temperature and enteric-coated to ensure a biologically active product. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Product details
- Is Discontinued By Manufacturer : No
- Product Dimensions : 2 x 3 x 5 inches; 1.2 ounces
- Item model number : SAMEBX
- Date First Available : January 10, 2004
- Manufacturer : Jarrow Formulas
- ASIN : B0013OULRO
- Country of Origin : USA
- Best Sellers Rank: #20,584 in Health & Household (See Top 100 in Health & Household)
- #338 in Multi-Enzyme Nutritional Supplements
- #341 in Multivitamins
- #1,933 in Diet & Sports Nutrition
- Customer Reviews:
Compare with similar items
This Item Jarrow Formulas SAMe 200 mg - 20 Tablets - Highest Concentration of Active S,S Form - Supports Joint Health, Liver Function, Brain Metabolism & Antioxidant Defense - 20 Servings | Recommendations | dummy | dummy | dummy | dummy | |
Try again! Added to Cart | Try again! Added to Cart | Try again! Added to Cart | Try again! Added to Cart | Try again! Added to Cart | Try again! Added to Cart | |
Price | -60% $7.41$7.41 List: $18.49 | $35.95$35.95 | -15% $23.99$23.99 List: $28.22 | -50% $30.88$30.88 List: $62.19 | $24.99$24.99 | $49.78$49.78 |
Price Per Unit | $0.37 / Count | $0.30 / Count | $0.40 / Count | $0.86 / Count | $0.42 / Count | $0.41 / Count |
Delivery | Get it as soon as Tuesday, Apr 2 | Get it as soon as Tuesday, Apr 2 | Get it as soon as Tuesday, Apr 2 | — | Get it as soon as Tuesday, Apr 2 | Get it as soon as Thursday, Apr 4 |
Customer Ratings | ||||||
Easy to swallow | 4.4 | 4.2 | 4.3 | 4.2 | 4.3 | 4.5 |
Pain relief | 3.2 | 3.5 | 3.2 | 3.5 | 3.3 | 3.8 |
Flavor | — | 4.2 | 4.0 | — | 3.5 | 4.3 |
Value for money | 3.5 | — | — | 3.8 | — | 4.5 |
Sold By | Amazon.com | eSupplements | Carlyle | JBGOODZ | EZ Melts | Nature's Trove |
keyword type | multi-enzymes-nutritional-supplements | multiple-vitamin-mineral-combinations | multiple-vitamin-mineral-combinations | multiple-vitamin-mineral-combinations | multiple-vitamin-mineral-combinations | multiple-vitamin-mineral-combinations |
form | Tablet,Tablets | Capsule | Tablet | Tablet | Tablet | Caplet |
flavor | Unflavored | — | — | No Artificial Flavors | Wild Berry | Unflavored |
size | 20 Servings (Pack of 1) | 120 Count (Pack of 1) | 60 Count (Pack of 1) | 36 Count (Pack of 1) | 60 Count (Pack of 1) | 60 Count (Pack of 2) |
weight | 0.07 pounds | 0.07 kilograms | 5.26 ounces | 0.15 pounds | 0.02 kilograms | 0 pounds |
age range | Adult | Adult | Adult | Adult | Adult | All Ages |
product benefit | Mood Support | — | — | Mood Support,Joint Support | Brain Health Support, Bone & Joint Support, Mood Support | Bone & Joint Support, Liver Health Support |
Important information
Safety Information
Individuals using prescribed medications such as antidepressants, including Seratonin Re-Uptake Inhibitors and MAO Inhibitors should consult a physician before using. Individuals with Parkinson's disease, bi-polar disorder or manic depression should not use SAM-e.This product is labelled to United States standards and may differ from similar products sold elsewhere in its ingredients, labeling and allergen warnings
Ingredients
S-Adenosyl Methionine (from 800 mg of SAMe Tosylate Disulfate), cellulose, glyceryl behenate, magnesium stearate (vegetable source), silicon dioxide, mannitol, sodium starch glycolate, enteric coating (modified cellulose, magnesium silicate, triethyl citrate, riboflavin)
Directions
Take 1 tablet 1 or 2 times per day on an empty stomach or as directed by your qualified healthcare professional.
Legal Disclaimer
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.
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Customer reviews
Customer Reviews, including Product Star Ratings help customers to learn more about the product and decide whether it is the right product for them.
To calculate the overall star rating and percentage breakdown by star, we don’t use a simple average. Instead, our system considers things like how recent a review is and if the reviewer bought the item on Amazon. It also analyzed reviews to verify trustworthiness.
Learn more how customers reviews work on AmazonCustomers say
Customers like the attention span, quality and effect of the nutritional supplement. For example, they mention it helps focus and stay alert, it makes thoughts clearer and it's worth it if it works. That said, some say it helps with anxiety and depression. That being said, opinions are mixed on sleep aid, and value.
AI-generated from the text of customer reviews
Customers are happy with the effect of the nutritional supplement on their mood. They say it makes them a little more calm, balanced, and helps with irritability. They also say it helps with mild depression, anxiety, and chronic fatigue. Some customers also mention that they feel more alert throughout the day and are happier.
"...Here are my experiences:-- I definitely feel more alert throughout the day and have had a happier, more optimistic inclination about the..." Read more
"...have to manage my chronic conditions, but Sam-e has definitely helped with the knee pain and it gives me an overall feeling of well-being despite my..." Read more
"...I have never experienced stomach pain from taking SAM-e. I am speculating that whatever neurotransmitter is being produced as the result of taking..." Read more
"...taking it for a few weeks, but at the same time, I notice that my mood is much better in the first half of the day..." Read more
Customers like the quality of the nutritional supplement. They say it works well and makes a difference with moods and joint pain. Some customers say it's worth a shot, but it doesn't work with everybody. It works gently with no side effects to help put them at ease. Customers also mention that it'll begin working right away and is easy to swallow.
"...***August, 2018 SAM-e is wonderful! I wish I had tried this years ago!..." Read more
"...It's easy to swallow and works best if taken on an empty stomach.The 400 mg strength is a capsule shaped pill also in blister packs...." Read more
"...Sam-e Begins working right away ...." Read more
"Noticed a difference right away it works better on an empty stomach but it also gives you an upset stomach if you take too much so be careful...." Read more
Customers like the side effects of the nutritional supplement. They mention that it has minimal side effects, and it also has benefits for joints and liver functions. Some say that the supplement has immediate, sharp effects that never made them sick. They also say that it works to reduce anxiety and depression.
"...However, it seemed to have immediate, salient effects on me, that I'm certain are not placebo since I expected to experience no effects until about..." Read more
"...The best thing, though, is the liver support I didn't realize I needed...." Read more
"...Give it a try! I didn't have any of the stomach upset issues. No side effects at all." Read more
"...-e has some side effects, as well as some undesirable interactions with certain drugs and cough medicines...." Read more
Customers have good things to say about the attention span of the supplement. They say, for example, they have more energy, better concentration, and a clearer head. Customers also say that it helps them focus and stay alert, and that it makes them think clearer. They also mention that their eye sight seems to improve. Overall, customers are happy with the product and recommend it to others.
"...(e.g. constant smile, better at holding eye contact, less stuttering/flustering).--..." Read more
"...sleepiness during the day, and the SAM-e seemed to really help me focus and stay alert...." Read more
"...As for side effects, not an issue; my eye sight seemed to improve and didn’t need to wear glasses as much, dreams, I’ve always dreamed a lot but..." Read more
"...This brand immediately improved my focus. I was able to catch up in my graduate classes. I was making jokes and laughing...." Read more
Customers say the nutritional supplement helps with energy levels. They also mention that it provides more clean energy within 2 days.
"...I feel so much better and have so much more energy when I take SAM-e that I don't think it's a placebo effect...." Read more
"...and have notice I am more focused and have more energy and seem to be in an overall better mood." Read more
"This product has SAVED MY LIFE. I noticed more clean energy within 2 days. I'm 6 weeks in and still feel amazing...." Read more
"...(more optimistic/less gloomy/increased energy which is a miracle in this weather)...." Read more
Customers are mixed about the value of the nutritional supplement. Some mention that it works great and saves them $30 a month, while others say that it's pretty expensive and a complete waste of money.
"...IT IS WORTH THE MONEY!" Read more
"...The downside to Sam-E is that it can be very expensive and not covered by any insurance since it's a vitamin supplement...." Read more
"...They're small and easy to swallow, well worth it." Read more
"...again has shown me exactly what has been missing - a better quality of life with less expense, no side effects...." Read more
Customers are mixed about the sleep aid. Some mention that it helps with sleep, while others say that it causes slight insomnia, diarrhea, and intestinal upset.
"...next few days, I experienced some of the side-effects of SAM-e: slight insomnia, diarrhea, and intestinal upset...." Read more
"...night since I have been taking SAM-e and I think it helps me get more refreshing sleep, which as a result means I wake up not feeling like I got hit..." Read more
"...I started to feel cloudy mentally and couldn't focus. It also made me extremely sleepy as well...." Read more
"...It was a real eyeopener. It made me fairly sleepy,at first, and it has definitely had an affect on my moods. I haven't felt this content in decades!..." Read more
Customers are dissatisfied with the pain relief of the nutritional supplement. They mention that it causes stomach pains, nausea, and headaches. Some say that it also causes mild discomfort and stiffness in the muscles. Overall, customers are not happy with the product's pain relief capabilities.
"...stuffed into a small bubble mailer that was clearly not protected from getting "squished."..." Read more
"...I forgot one day and took one after eating breakfast. Yuck, my stomach felt very gross. If I take them on an empty stomach, no problem!" Read more
"...I experienced some of the side-effects of SAM-e: slight insomnia, diarrhea, and intestinal upset...." Read more
"...The meds listed above all caused increased anxiety, no appetite which also caused slow growth, and one just stopped working after a while...." Read more
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Top reviews
Top reviews from the United States
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Three years ago, I started taking the Nature's Made brand (very commonly found at a local pharmacy) for a short period of time. Folks online reported that effective combating of depression required about 800mg to 1600mg per day in order to see an effect. I was on this regimen for about two weeks and became EXTREMELY PARANOID AND ANXIOUS about the most irrational of things.
About a month ago, I re-researched into Sam-E again. New information and user testimonials had come out over the last few years about differences in brand effectiveness, daily dosage, etc. As I alluded to before, some folks may need a high dosage like 1600mg to see a difference. However, I noticed that I only need a fraction of that amount in order to feel better.
I started off with Nature's Made and took about a much lower dosage at 400mg (200mg in the morning and 200mg in the afternoon). I felt great after the morning dosage, but the increase in anxiety crept up shortly after the afternoon dosage. No paranoia this time around though. This forced me to think about scaling the daily dosage back to 200mg per day (once in the morning only). After doing so, I started feeling great!
Additionally, I have been taking my Sam-E with a B-Complex in the morning. Per Dr. Andrew Weil (which you can search online and read for yourself), he recommends the following to be used alongside Sam-E: "Take a daily multivitamin supplement that provides 400 mcg of folic acid, at least 50 mg of vitamin B6 and 50 mcg of B12 (along with the rest of the B-complex)." Many folks also recommend that you stay very hydrated as another means of helping Sam-E do its job.
Here are my experiences:
-- I definitely feel more alert throughout the day and have had a happier, more optimistic inclination about the day-to-day stuff in life.
-- Similarly, I notice that I don't need as much coffee during the day. Before Sam-E, I needed at least a few (large) cups per day. Now, one cup of coffee in the morning is more than enough.
-- I definitely feel as if I sleep better and have more drive to get out of bed in the mornings. Like the Chicken or the Egg argument, I'm sure that getting a more restful night's of sleep is also helping me feel better throughout the day.
-- I used to constantly fall asleep during Movies and TV shows in the early evenings. Sam-E has given me an extra boost of energy where I don't prematurely fall asleep.
-- Although many have said that Sam-E doesn't drastically help with their anxiety, I noticed that by taming depression, my anxiety has also been reduced. For example, I have felt an increase in confidence; the extra spark of energy has allowed me to give off a healthier vibe towards others (e.g. constant smile, better at holding eye contact, less stuttering/flustering).
-- I have also felt motivated to complete my (often mundane) day-to-day tasks, such as cleaning the house, doing the dishes, cook dinner, etc. Similarly, at work, I have seen an increase in successfully meeting my daily responsibilities since taking Sam-E.
The downside to Sam-E is that it can be very expensive and not covered by any insurance since it's a vitamin supplement. This forced me to research into cheaper options for Sam-E. Luckily, the Jarrow's brand is highly raved by other Amazon users AND the price is substantially less than buying the Nature's Made version at a local store. I have felt the same positive effects from Jarrow's as I did when using Nature's Made. The only thing to beware is that a few people have said that the effects ARE different between the two brands (both positive and negative) - again, your mileage my vary.
Also, Sam-E isn't a "magic bullet" solution. Sam-E can only do so much if you're out of shape and/or are sleep deprived. For example, I am a late-night owl and if I only get a few hours of sleep, I wake up feeling groggy (just as any normal person would). You have to be realistic about Sam-E; it can enable you to feel better but the problem won't entirely go away unless you choose to make other lifestyle changes.
*BEWARE OF THE PACKAGING/SHIPPING*
The last thing I wanted to point out is to beware of the packaging. I ordered my Jarrow's 200mg directly from Amazon and the packaging was EXTREMELY POOR; the vitamins were stuffed into a small bubble mailer that was clearly not protected from getting "squished." When it arrived, the box inside was compressed into half its size (presumably from having other packages sit on top of it) AND it caused half of the blister packs to break open (leaving the vitamins exposed into the air). As other reviewers have mentioned, Sam-E is very sensitive to air/moisture changes, so I was forced to throw away any tablets that were already exposed.
FYI, other vendors will put the vitamins into a small cardboard box stuffed with large air bubbles to protect the item from getting "squished." Granted, other vendors are more expensive but I'm also not throwing away wasted tablets. Although I won't dock stars away from the product (since it's not Jarrow's fault), it is absolutely something that buyers need to be aware of.
Note: I am not a licensed clinical professional. Any information provided above is meant to be used for informational purposes only and should not replace the advice of an actual physician.
After 3 doses, 12hrs apart, I have begun to feel my mood lighten and the mobility of and pain in my knees is much better! I can perform my physical therapy exercises with little problem now!
Side effects so far: I began taking SAM-e one evening and the next morning I awoke with a headache, but I continued taking it the next morning and evening. This morning I awoke with only a slight headache. I slept deeply and well! It is hard to tell if it has affected my active IBS condition, but it is no worse than usual so far.
I am very sensitive to medications, chemicals and environmental changes. I have had fibromyalgia, IBS and psoriasis for years. I took Savella for fibromyalgia for just over a year and have had a certain amount of relief as long as I pace my activity and am careful about what I carry, what and how I reach or pick something up and refrain from holding my arms over my head to perform a task. I also practice pre-&post-activity rest. SAM-e has affected my mood much like the Savella did. I am cautious about getting too excited, but this does look promising!
***August, 2018 SAM-e is wonderful! I wish I had tried this years ago! I still have to manage my chronic conditions, but Sam-e has definitely helped with the knee pain and it gives me an overall feeling of well-being despite my challenges.I like this brand because each tablet is individually sealed and I am confident that my doses are fresh and consistent. I am so thankful for SAM-e! Thanks, Jarrow, for the good product, too! I just subscribed to receive SAM-e automatically each month.
Top reviews from other countries
Avant, j'avais essayé la marque "Now". Celui ci est un peu plus cher mais 1000 fois mieux!
Ne perdez pas votre temps avec l'autre!
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