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Jarrow Formulas SAMe 200 mg - 20 Tablets - Highest Concentration of Active S,S Form - Supports Joint Health, Liver Function, Brain Metabolism & Antioxidant Defense - 20 Servings

4.4 4.4 out of 5 stars 1,087 ratings

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Unflavored
20 Count (Pack of 1)

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About this item

  • to: Highest Concentration of Active S,S Form - The S,S structure is the biologically active form of SAMe. The formula is made naturally by fermentation & processed without chemical solvents to preserve 68-80% S,S SAMe.
  • to: Joint Health, Liver Function & Antioxidant Defense - SAMe supports the production of healthy connective tissue.* Plus, SAMe metabolism supports the synthesis of glutathione, which is critical for antioxidant defenses and liver functions.*
  • Brain Metabolism - SAMe methylation reactions are involved in the synthesis of phosphatidylcholine and neurotransmitters such as dopamine, norepinephrine, and serotonin.*
  • to: Enteric Coating - SAMe provides 200 mg SAMe (net yield) from 400 mg of SAMe tosylate disulfate. It is manufactured under low temperature and low humidity, and enteric-coated to ensure a biologically active product.*
  • to: Superior Science, Smarter Formulas - Informed by strong scientific research, Jarrow Formulas products are carefully crafted to ensure you get the benefit of each and every vitamin, mineral and supplement.

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$7.41 ($0.37/Count)
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From the brand


From the manufacturer

Mental Wellness

100% dedicated to getting every formula right

innovation

pill and capsule collage

Our formulations are carefully crafted and informed by strong scientific research. We are 100% dedicated to getting every formula right.

Our mental wellness supplements include ingredients such as Magtein, Cognizin Citicoline and Sharp-PS that support brain health, certain aspects of cognition, positive mood, and deep sleep.*

We evaluate ingredient purity and only work with suppliers who follow Current Good Manufacturing Practices (cGMP) for our capsules, tablets, softgels and powder formulations.

Empowering your body to help itself
magmind brain health theanine 200 ultra strength sam400 extra strength neuro optimizer brain health and function ashwagandha adaptogen alpha gpc choline source
MagMind Brain Health Theanine 200 SAMe 400 Neuro Optimizer Ashwagandha Alpha GPC
Customer Reviews
4.6 out of 5 stars
4,023
4.5 out of 5 stars
2,286
4.4 out of 5 stars
592
4.5 out of 5 stars
1,023
4.5 out of 5 stars
1,781
4.5 out of 5 stars
527
Primary Benefit Supports Brain Health, Function &​ Memory^*​ ^In healthy adults​ Promotes Relaxation*​ Supports Balanced Mood, Joint Health & Liver Function*​ Supports Neuron & Normal Stress Response*​ Supports Normalized Resistance to Mental & Physical Stress*​ Support Brain Function*​
Key Ingredients Magtein Magnesium​ L-Theanine​ S-Adenosyl Methionine​ Cognizin Citicoline, Sharp-PS Phosphatidylserine​ Ashwagandha Extract​ Alpha GPC​
No Major Allergens
Form Type Veggie Capsule Veggie Capsule Tablet Capsule Veggie Capsule Veggie Capsule
Size Options 90 60 30 & 60 120 120 60
formulating health since 1977

Product Description

We use superior science to make smarter formulas like Jarrow Formulas� SAMe 200, a metabolite of methionine (an essential amino acid). It provides a full 200 mg SAMe (net yield) from 400 mg of SAMe tosylate disulfate. The S,S structure is the biologically active form of SAMe. This formula is made naturally by fermentation and processed without chemical solvents to preserve 68-80% S,S SAMe. SAMe supports the production of healthy connective tissue.* Plus, SAMe metabolism supports the synthesis of glutathione, which is critical for antioxidant defenses and liver functions.* SAMe methylation reactions are involved in the synthesis of phosphatidylcholine and neurotransmitters such as dopamine, norepinephrine, and serotonin.* The formula is manufactured under low temperature and enteric-coated to ensure a biologically active product. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Product details

  • Is Discontinued By Manufacturer ‏ : ‎ No
  • Product Dimensions ‏ : ‎ 2 x 3 x 5 inches; 1.2 ounces
  • Item model number ‏ : ‎ SAMEBX
  • Date First Available ‏ : ‎ January 10, 2004
  • Manufacturer ‏ : ‎ Jarrow Formulas
  • ASIN ‏ : ‎ B0013OULRO
  • Country of Origin ‏ : ‎ USA
  • Customer Reviews:
    4.4 4.4 out of 5 stars 1,087 ratings

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Jarrow Formulas SAMe 200 mg - 20 Tablets - Highest Concentration of Active S,S Form - Supports Joint Health, Liver Function, Brain Metabolism & Antioxidant Defense - 20 Servings
Jarrow Formulas SAMe 200 mg - 20 Tablets - Highest Concentration of Active S,S Form - Supports Joint Health, Liver Function, Brain Metabolism & Antioxidant Defense - 20 Servings
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Price-60% $7.41
List:$18.49
$35.95-15% $23.99
List:$28.22
-50% $30.88
List:$62.19
$24.99$49.78
Price Per Unit$0.37 / Count$0.30 / Count$0.40 / Count$0.86 / Count$0.42 / Count$0.41 / Count
Delivery
Get it as soon as Tuesday, Apr 2
Get it as soon as Tuesday, Apr 2
Get it as soon as Tuesday, Apr 2
Get it as soon as Tuesday, Apr 2
Get it as soon as Thursday, Apr 4
Customer Ratings
Easy to swallow
4.4
4.2
4.3
4.2
4.3
4.5
Pain relief
3.2
3.5
3.2
3.5
3.3
3.8
Flavor
4.2
4.0
3.5
4.3
Value for money
3.5
3.8
4.5
Sold By
Amazon.com
eSupplements
Carlyle
JBGOODZ
EZ Melts
Nature's Trove
keyword type
multi-enzymes-nutritional-supplements
multiple-vitamin-mineral-combinations
multiple-vitamin-mineral-combinations
multiple-vitamin-mineral-combinations
multiple-vitamin-mineral-combinations
multiple-vitamin-mineral-combinations
form
Tablet,Tablets
Capsule
Tablet
Tablet
Tablet
Caplet
flavor
Unflavored
No Artificial Flavors
Wild Berry
Unflavored
size
20 Servings (Pack of 1)
120 Count (Pack of 1)
60 Count (Pack of 1)
36 Count (Pack of 1)
60 Count (Pack of 1)
60 Count (Pack of 2)
weight
0.07 pounds
0.07 kilograms
5.26 ounces
0.15 pounds
0.02 kilograms
0 pounds
age range
Adult
Adult
Adult
Adult
Adult
All Ages
product benefit
Mood Support
Mood Support,Joint Support
Brain Health Support, Bone & Joint Support, Mood Support
Bone & Joint Support, Liver Health Support

Important information

Safety Information

Individuals using prescribed medications such as antidepressants, including Seratonin Re-Uptake Inhibitors and MAO Inhibitors should consult a physician before using. Individuals with Parkinson's disease, bi-polar disorder or manic depression should not use SAM-e.This product is labelled to United States standards and may differ from similar products sold elsewhere in its ingredients, labeling and allergen warnings

Ingredients

S-Adenosyl Methionine (from 800 mg of SAMe Tosylate Disulfate), cellulose, glyceryl behenate, magnesium stearate (vegetable source), silicon dioxide, mannitol, sodium starch glycolate, enteric coating (modified cellulose, magnesium silicate, triethyl citrate, riboflavin)

Directions

Take 1 tablet 1 or 2 times per day on an empty stomach or as directed by your qualified healthcare professional.

Legal Disclaimer

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

Looking for specific info?

Customer reviews

4.4 out of 5 stars
4.4 out of 5
1,087 global ratings

Customers say

Customers like the attention span, quality and effect of the nutritional supplement. For example, they mention it helps focus and stay alert, it makes thoughts clearer and it's worth it if it works. That said, some say it helps with anxiety and depression. That being said, opinions are mixed on sleep aid, and value.

AI-generated from the text of customer reviews

126 customers mention110 positive16 negative

Customers are happy with the effect of the nutritional supplement on their mood. They say it makes them a little more calm, balanced, and helps with irritability. They also say it helps with mild depression, anxiety, and chronic fatigue. Some customers also mention that they feel more alert throughout the day and are happier.

"...Here are my experiences:-- I definitely feel more alert throughout the day and have had a happier, more optimistic inclination about the..." Read more

"...have to manage my chronic conditions, but Sam-e has definitely helped with the knee pain and it gives me an overall feeling of well-being despite my..." Read more

"...I have never experienced stomach pain from taking SAM-e. I am speculating that whatever neurotransmitter is being produced as the result of taking..." Read more

"...taking it for a few weeks, but at the same time, I notice that my mood is much better in the first half of the day..." Read more

94 customers mention83 positive11 negative

Customers like the quality of the nutritional supplement. They say it works well and makes a difference with moods and joint pain. Some customers say it's worth a shot, but it doesn't work with everybody. It works gently with no side effects to help put them at ease. Customers also mention that it'll begin working right away and is easy to swallow.

"...***August, 2018 SAM-e is wonderful! I wish I had tried this years ago!..." Read more

"...It's easy to swallow and works best if taken on an empty stomach.The 400 mg strength is a capsule shaped pill also in blister packs...." Read more

"...Sam-e Begins working right away ...." Read more

"Noticed a difference right away it works better on an empty stomach but it also gives you an upset stomach if you take too much so be careful...." Read more

18 customers mention14 positive4 negative

Customers like the side effects of the nutritional supplement. They mention that it has minimal side effects, and it also has benefits for joints and liver functions. Some say that the supplement has immediate, sharp effects that never made them sick. They also say that it works to reduce anxiety and depression.

"...However, it seemed to have immediate, salient effects on me, that I'm certain are not placebo since I expected to experience no effects until about..." Read more

"...The best thing, though, is the liver support I didn't realize I needed...." Read more

"...Give it a try! I didn't have any of the stomach upset issues. No side effects at all." Read more

"...-e has some side effects, as well as some undesirable interactions with certain drugs and cough medicines...." Read more

15 customers mention15 positive0 negative

Customers have good things to say about the attention span of the supplement. They say, for example, they have more energy, better concentration, and a clearer head. Customers also say that it helps them focus and stay alert, and that it makes them think clearer. They also mention that their eye sight seems to improve. Overall, customers are happy with the product and recommend it to others.

"...(e.g. constant smile, better at holding eye contact, less stuttering/flustering).--..." Read more

"...sleepiness during the day, and the SAM-e seemed to really help me focus and stay alert...." Read more

"...As for side effects, not an issue; my eye sight seemed to improve and didn’t need to wear glasses as much, dreams, I’ve always dreamed a lot but..." Read more

"...This brand immediately improved my focus. I was able to catch up in my graduate classes. I was making jokes and laughing...." Read more

8 customers mention8 positive0 negative

Customers say the nutritional supplement helps with energy levels. They also mention that it provides more clean energy within 2 days.

"...I feel so much better and have so much more energy when I take SAM-e that I don't think it's a placebo effect...." Read more

"...and have notice I am more focused and have more energy and seem to be in an overall better mood." Read more

"This product has SAVED MY LIFE. I noticed more clean energy within 2 days. I'm 6 weeks in and still feel amazing...." Read more

"...(more optimistic/less gloomy/increased energy which is a miracle in this weather)...." Read more

47 customers mention31 positive16 negative

Customers are mixed about the value of the nutritional supplement. Some mention that it works great and saves them $30 a month, while others say that it's pretty expensive and a complete waste of money.

"...IT IS WORTH THE MONEY!" Read more

"...The downside to Sam-E is that it can be very expensive and not covered by any insurance since it's a vitamin supplement...." Read more

"...They're small and easy to swallow, well worth it." Read more

"...again has shown me exactly what has been missing - a better quality of life with less expense, no side effects...." Read more

17 customers mention7 positive10 negative

Customers are mixed about the sleep aid. Some mention that it helps with sleep, while others say that it causes slight insomnia, diarrhea, and intestinal upset.

"...next few days, I experienced some of the side-effects of SAM-e: slight insomnia, diarrhea, and intestinal upset...." Read more

"...night since I have been taking SAM-e and I think it helps me get more refreshing sleep, which as a result means I wake up not feeling like I got hit..." Read more

"...I started to feel cloudy mentally and couldn't focus. It also made me extremely sleepy as well...." Read more

"...It was a real eyeopener. It made me fairly sleepy,at first, and it has definitely had an affect on my moods. I haven't felt this content in decades!..." Read more

36 customers mention5 positive31 negative

Customers are dissatisfied with the pain relief of the nutritional supplement. They mention that it causes stomach pains, nausea, and headaches. Some say that it also causes mild discomfort and stiffness in the muscles. Overall, customers are not happy with the product's pain relief capabilities.

"...stuffed into a small bubble mailer that was clearly not protected from getting "squished."..." Read more

"...I forgot one day and took one after eating breakfast. Yuck, my stomach felt very gross. If I take them on an empty stomach, no problem!" Read more

"...I experienced some of the side-effects of SAM-e: slight insomnia, diarrhea, and intestinal upset...." Read more

"...The meds listed above all caused increased anxiety, no appetite which also caused slow growth, and one just stopped working after a while...." Read more

Rotten Capsule
1 Star
Rotten Capsule
The picture speaks for itself. I had taken more than half of the capsules when I had that unpleasant surprise. Product was stored as recomended and with other vitamins and medicines, so you can rule out poor storage as the cause for product going bad (even the other capsures look fine) Based on many positive reviews one could think this was only bad luck or a bad batch but to me it shows, at a minimum, lack of quality control by the manufacturer. The good news is that it seems to be unavailable at amazon.
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Top reviews from the United States

Reviewed in the United States on October 15, 2013
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Reviewed in the United States on April 22, 2018
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Reviewed in the United States on March 25, 2015
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Top reviews from other countries

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kramski
5.0 out of 5 stars Excellent
Reviewed in France on May 24, 2022
Flavor Name: UnflavoredSize: 20 Count (Pack of 1)Verified Purchase
7 people found this helpful
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Claudia S.
5.0 out of 5 stars Da ricomprare
Reviewed in Italy on August 24, 2019
Flavor Name: UnflavoredSize: 60 Count (Pack of 1)Verified Purchase
Amazon Customer
3.0 out of 5 stars Crushed box with ruptured blister packs = wasted supplement
Reviewed in Australia on January 17, 2022
Flavor Name: UnflavoredSize: 60 Count (Pack of 1)Verified Purchase
Mina
2.0 out of 5 stars Quantité par boîtes
Reviewed in France on December 7, 2023
Flavor Name: UnflavoredSize: 20 Count (Pack of 1)Verified Purchase

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