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Changing the Course of Autism: A Scientific Approach for Parents and Physicians Paperback – Illustrated, May 11, 2007

by Bryan Jepson (Author), Katie Wright (Foreword), Jane Johnson (Collaborator)

4.6 58 ratings

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This book shows that autism can be treated by reducing the neurological inflammation that is part of the disease process, rather than simply masking the symptoms with drugs like Ritalin and Prozac. The authors have have seen autistic behaviors improve dramatically or disappear completely with appropriate medical treatment. The book reviews the medical literature regarding the biological nature of the disease, including the potential connection between vaccines and autism. The foreword is by Katie Wright, whose parents―Bob and Suzanne Wright―founded Autism Speaks.

Print length

358 pages
Language

English
Publisher

Sentient Publications
Publication date

May 11, 2007
Dimensions

6.13 x 1.01 x 8.75 inches
ISBN-10

1591810612
ISBN-13

978-1591810612
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Editorial Reviews

Review

Twenty years ago autism was rare: today it's prevalent, making Changing the Course of Autism: A Scientific Approach to Treating Your Autistic Child even more essential to any public or college-level health collection. This book challenges many conventional beliefs about autism's origins and diagnosis, and suggests it has roots in the environment. Chapters cover nutritional and disease models of autism and offer important medical insights on autism's many influences. It's a key autism survey any serious health collection needs; particularly those catering to parents. ― Midwest Book Review

Once viewed as rare and unusual, autism is now considered an epidemic with the latest Centers for Disease Control and Prevention findings reporting that one in 150 children in the United States now has autism. The parent of an autistic child, Jepson (founder, Children’s Biomedical Ctr. of Utah) encourages physicians and parents to view autism 'as a medical illness, not just a behavior disorder.' He discusses the neurological, gastrointestinal, genetic, and environmental issues that complicate our understanding of autism. His book is meant to be used as an overview for the layperson, not as a step-by-step guide on how to treat autism. Although there are agreed-upon common treatment approaches, each autistic child is unique. Jepson makes clear that with proper medical oversight, the autistic child can improve, often dramatically. Recommended as a comprehensive reference resource on autism in consumer health collections.

― Library Journal

'Calling it a developmental disorder is like calling a brain tumor a headache. Autism is merely one symptom of an underlying disease process that affects the immunological system, the gastrointestinal system, and the toxicological system, as well as the neurological system.'

If you've searched for biomedical treatments, chances are you've encountered a glaring lack of knowledge or even outright skepticism. Dr. Jepson wrote this book to help overcome such obstacles.

Changing the Course of Autism is radically comprehensive. Dr. Jepson has consolidated all the current research on thimerosal, immune system dysfunction, gut disease and environmental toxins. He explains the biochemistry of autism and discusses how biomedical treatments work. His goal is to educate mainstream physicians about the medical basis of autism, but he also writes for parents so they can understand the biological rationale behind the treatment strategies for their children.

The scientific information is extensive but there is plenty of understandable content and readers can skip to whatever sections suit their needs. Dr. Jepson has truly created an indispensable one-stop reference for autism's biomedical issues.

― Autism/Asperger's Digest Magazine

This book will be the new PDR of autism for parents and physicians. Incredibly well referenced and easy to understand, it challenges long-held beliefs about this condition and introduces us to the new medical model of autism. An important book that every professional and family member who deals with autism must own.
-- Lee Grossman, president and CEO, Autism Society of America

Dr. Bryan Jepson demystifies the disorder by providing the most up-to-date information on symptoms, detection, diagnosis, treatment, and the impact of the disorder on families of individuals with autism. Based on Dr. Jepson’s extensive research and clinical observations, this book answers myriad questions about autism with authority and compassion.

-- Doreen Granpeesheh, BCBA, executive director, Center for Autism and Related Disorders

The idea that the suffering of autism could be rooted in environmental injuries poses a huge challenge to medicine, science and society. Opening our hearts and minds to fresh thinking is the only way forward. Dr. Jepson's information-filled book moves the reader through the discomfort of painful news to a framework for constructive responses.
-- Martha R. Herbert

Review

Board-certified emergency medical doctor and parent of an autism spectrum child Bryan Jepson, M.D. presents Changing the Course of Autism: A Scientific Approach for Parents and Physicians, a scientific scrutiny that re-examines commonly held beliefs about autism spectrum disorder, along with Jane Johnson, whose expertise lies in the field of researching and treating autism in children.

Changing the Course of Autism takes the bold stance that autism is not solely caused by genetic factors, but rather a combination of genetic and environmental factors - an abundance of toxicity in the environment combined with autistic individuals' reduced ability or inability to detoxify. The sudden epidemic of autism in today's society (1 in 150 children has been diagnosed) underscores that environmental factors must be at work, since a disease that is solely genetic is not likely to produce a similar surge. Chapters further explore possible environmental causes of autism, and ways to treat autism and help children recover. Written in plain terms for parents, caretakers, and medical personnel alike, Changing the Course of Autism is an absolute must-read for new or expecting parents with a history of autism, or who wish to prepare themselves to defend their child from an onslaught of environmental toxins in today's unfortunately polluted world. Highly recommended.

Review

Once viewed as rare and unusual, autism is now considered an epidemic with the latest Centers for Disease Control and Prevention findings reporting that one in 150 children in the United States now has autism. The parent of an autistic child, Jepson (founder, Children's Biomedical Ctr. of Utah) encourages physicians and parents to view autism "as a medical illness, not just a behavior disorder." He discusses the neurological, gastrointestinal, genetic, and environmental issues that complicate our understanding of autism. His book is meant to be used as an overview for the layperson, not as a step-by-step guide on how to treat autism. Although there are agreed-upon common treatment approaches, each autistic child is unique. Jepson makes clear that with proper medical oversight, the autistic child can improve, often dramatically. Recommended as a comprehensive reference resource on autism in consumer health collections.

From the Publisher

A once rare disease, autism is now a worldwide epidemic affecting 1.8 million American children, making it the most common developmental disability-more common than Down syndrome, cerebral palsy, and mental retardation combined. Changing the Course of Autism has the potential to revolutionize the way this disease is perceived and managed by showing that autism can be treated as a medical disease, rather than a behavioral disorder. In this groundbreaking book, the authors describe specific methods that they have used to successfully diagnose and treat the underlying medical conditions of autistic children.

The foreword is by Katie Wright Hildebrand, whose parents, Bob and Suzanne Wright, founded the organization Autism Speaks after Katie's son was diagnosed with autism. As CEO of NBC/Universal, Bob made Autism Speaks the biggest autism organization in the country, and Katie and her parents have worked tirelessly to raise autism awareness.

About the Author

BRYAN JEPSON, M.D., graduated from the University of Utah Medical School in 1995 and completed residency training in Grand Rapids, Michigan in 1998. He is Board certified in emergency medicine. In 2001, his second son was diagnosed with autism. Over the course of that year, he and his wife Laurie began exploring treatment options and found that the medical community knew very little about the cause, the treatment, or the prognosis of this disease. After a year of research, the couple established a clinic in Utah where autistic children could receive the most up-to-date care available. From 2002-2005, their non-profit Children's Biomedical Center of Utah raised awareness throughout the intermountain West concerning issues related to autism and other childhood developmental disorders. Dr. Jepson treated hundreds of children on the autism spectrum and enjoyed the experience of watching them improve.

Because he was a leading specialist in the field, Dr. Jepson was recruited to join the team at Thoughtful House Center for Children, a multidisciplinary clinic dedicated to caring for children with autism and related conditions. The Thoughtful House is designed to integrate biomedical, gastrointestinal, and educational intervention into a coordinated effort, and to use this model to perform clinical research. Dr. Jepson is now the Director of Medical Services there.

He lives in Austin, Texas, with Laurie and their two sons.

JANE JOHNSON became interested in medical treatment for learning disabilities in 2000, when one of her children was diagnosed with non-verbal learning disorder (NLD). In her effort to educate herself, she became more and more alarmed at the epidemic growth of the prevalence of developmental disorders. She is the Co-Managing Director of the Board of Directors of Thoughtful House. She lives in New York City with her husband and her three children.

Product details

Publisher ‏ : ‎ Sentient Publications; Illustrated edition (May 11, 2007)
Language ‏ : ‎ English
Paperback ‏ : ‎ 358 pages
ISBN-10 ‏ : ‎ 1591810612
ISBN-13 ‏ : ‎ 978-1591810612
Item Weight ‏ : ‎ 1.09 pounds
Dimensions ‏ : ‎ 6.13 x 1.01 x 8.75 inches

Best Sellers Rank: #1,427,960 in Books (See Top 100 in Books)
- #1,335 in Autism Spectrum Disorder
- #34,774 in Psychology & Counseling

Customer Reviews:
4.6 58 ratings

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Bryan Jepson
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Bryan Jepson is the father of three children, two of whom have autism. He is a board-certified emergency medicine physician but also spent nine years treating children with autism and looking for biomedical solutions to the disorder. He was the founder of the non-profit Children's Biomedical Center of Utah in 2002 and was part of a team that established the Thoughtful House Center for Children (currently the Johnson Center for Child Health and Development) in Austin, Texas in 2006. He has authored two books about autism. One is entitled "Changing the Course of Autism: a scientific approach for parents and physicians," which is a non-fiction exploration of the research behind the biological origins of autism and various treatment modalities that are in use. The second is a novel entitled "The Record Player"--a story that follows a family's struggles as they come to terms with their son's diagnosis, look for treatment options and ultimately help him find his unique contribution. You can contact Bryan Jepson at bryjep3son@gmail.com.
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Jane Johnson
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Jane Johnson is the Managing Director of the Autism Research Institute, and the co-author of Dr. Bryan Jepson's "Changing the Course of Autism; A Scientific Approach for Parents and Physicians," and the co-editor, with Anne Van Rensselaer, of "Families of Adults With Autism; Stories and Advice for the Next Generation" and "Siblings: The Autism Spectrum Through our Eyes." She lives in New York City.
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R. Swinney

The most important book I have purchased in the last 10 years

Reviewed in the United States on September 12, 2007

Verified Purchase

If you are pregnant or have a child less than 1 year of age -- READ THIS BOOK!

The information in this book WILL change what you do about early childhood vaccination.
The information in this book MAY help you prevent your child from developing regressive autism.

As a residency trained, board certified emergency medicine physician, I am (both by nature and training) a skeptic. Throughout my medical career, I have been pro-vaccination. I have personally administered more than 1000 vaccinations, and have supervised the administration of more than 10,000 doses of vaccine -- including cholera, yellow fever, Japanese encephalitis and plague vaccines. My 14 year old received every recommended childhood vaccine on schedule. Since then, two of the "safe" vaccines (oral polio and whole cell pertussis) that the Centers for Disease Control and Prevention (CDC) recommended at the time have fallen from favor because of proven catastrophic (albeit rare) complications.

In the last 14 years, the CDC has made a number of changes and additions to the recommended childhood vaccine schedule. I purchased "Changing the Course of Autism" with the intent of systematically debunking it to put my wife at ease before we began vaccinating our infant daughter. To my surprise, I found the text to be a scholarly, thorough, even-handed analysis of the current controversy about vaccinations and autism. The more I researched known pro-vaccine sources (e.g. CDC, National Institutes of Health, etc.) to debunk the book, the more I realized that the authors had collected a wealth of credible scientific evidence that supports the theory that the recent significant increase in the number of childhood vaccinations may be directly related to the recent dramatic increase in cases of autism in the U.S., the U.K., Japan and other developed countries. The most damning case is made against MMR - the measles-mumps-rubella vaccine currently recommended by the CDC for administration at 1 year of age.

The information in this book is VITAL to making an informed decision about childhood vaccination.

This is the most important book I have purchased in the last 10 years. It has fundamentally changed my perspective on childhood vaccinations and helped me determine which vaccinations my child WILL NOT RECEIVE. To date, I have purchased 70 copies of this book to give to pediatricians and other fellow physicians, nurses, new parents and parents of autistic children.

Richard S. Swinney MD
Fellow of the American Academy of Emergency Medicine

150 people found this helpful

Helpful

H. Martin

Must read if you care for someone with autism -- or who is at risk

Reviewed in the United States on February 26, 2008

Verified Purchase

If you care for an autistic* child (or someone older) then this book is a must read -- several times, until you thoroughly understand the science involved in this condition and until someone writes an update in a few years, as the science grows.

*Autistic Spectrum Disorders, PDD, (including 'regressive' autism in children who initially developed normally.)

[If there is a better book -- or one even nearly as good -- PLEASE leave a review pointing the way to that book since I want to read it too. This and the Jaquelyn McCandless' book, "Children with Starving Brains: A Medical Treatment Guide for Autism Spectrum Disorders are the best and you should read both.]

Dr. Jepson is quite simple a scientist AND a physician who is trying to learn everything *he* can about autism, and to teach what every parent and treating physician needs to understand as a basis for beginning to help those with autism.

In this book he has provided a primer on the science needed to understand autism from a medical view point and on the current medical treatments and how they might work or be improved.

This is a book any literate (or really determined) parent can read, while at the same time presenting the scientific documentation so enable a physician to use it as a primer on the current debates and state of knowledge.

When deciding "can I read this book", consider it to be roughly at the same level as high school or college freshman biology in raw difficulty but remember that likely you are motivated to understand this disease far more than you ever were in high school.

Those who gave it low ratings as 'unscientific' quite simple never read this book, since practically every page is a discussion of biochemistry, immunology, and/or the scientific literature, both in support and in opposition to every major theory of autism and its treatment.

Jepson warns parents and physicians to seek the science. He is NOT a "mercury causes it" fanatic, but instead (for example) presents the science for and against mercury being a contributing factor.

He leads with the primary known risk factor and reminds of this throughout the book: autism has a strong genetic component.

He also points out that autism is on the rise (now estimated by the CDC at between 1 in 150 or 1 in 165) -- diagnostic changes and anomalies do NOT account for the increase of the last 20 years -- and that purely genetic diseases do not exhibit "epidemic" characteristics.

Jepson's only consistent "points of view" or biases are these:

1) Autism has a STRONG genetic component
(e.g., monozyotic twins incur it far more frequently but not
universally than either fraternal twins or other siblings)

2) Autism is more than just genetic and is a complex condition
likely to have several 'causes' which affect those with the
genetic predisposition.

3) Other (than neurological) conditions are commonly seen in
conjunction with autism, and might either be more closely
related to the root causes or environmental factors which
cause autism to express so tragically. (Intestinal disorders
being the most common.)

4) Finding a way to TREAT the babies that is safe and scientifically
supportable, driven by neither fads nor hindered by refusal to
really LOOK at and UNDERSTAND what the current scientific
studies indicate and do NOT indicate.

There is much more research to be done on autism -- read this book if you care for someone who has autism, or who may have it.

Give this book to your physician, or if you are a physician yourself, then recommend it to your friends AFTER you have read it and determined for yourself that it is indeed scientific.

15 people found this helpful

Helpful

United1981

good but hard to understand sometimes if youre not a DR

Reviewed in the United States on June 21, 2012

Verified Purchase

This was the first book i bought on Autism.My daughter was just diagnosed.If your more to the biomedical ave this probably inst the right book.It is hard to get sometimes if you arent a DR,but i kept on reading and did get alot of informative information.It is well written and hes a very smart man thats for sure.

Update.

In all fairness I've decided to write an update on the book. When I had originally bought this book I was new to autism ,and my daughter had been diagnosed two weeks prior.Now that I'm more familiar with some of the terms such as methylation,mitochondria etc I really like the book,I've read it three times now front to back and have important tidbits I miss every time I re read it. I have yet to find a book that tells you what's exactly going on with the body and helpful info on how to fix it.

5 people found this helpful

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Top reviews from other countries

Alexandra Trottier

Interesting read

Reviewed in Canada on October 25, 2019

Verified Purchase

Good read to research and learn about the topic

Amazon Customer

Excellent

Reviewed in India on October 22, 2016

Verified Purchase

Excellent

Clair

A must read

Reviewed in the United Kingdom on August 1, 2010

Verified Purchase

A brilliant book full of good information for de-bunking a lot of the epidemiological propoganda out there. The book focuses on real science from a wide range of research scientists. I love the authors honesty about his own presumptions about parents of vaccine damaged children (we're all crazy, wild eyed idiots in denial) before being forced to confront the real issues with his son.
I only wish every doctor in the country would read this book.

6 people found this helpful

Lindosland

Excellent, but still not the whole story I suspect

Reviewed in the United Kingdom on July 30, 2014

Verified Purchase

In the UK we are very much fed the story that autism is a 'developmental' disorder, that it is probably mostly genetic, and that mercury and vaccines are in no way to blame. This book is a refreshing antidote to that propaganda, and unlike many such books it is not selling a particular 'cure' but presents a wealth of well referenced information and based on research and epidemiological studies. His conclusions: Is there an epidemic, yes. Is this simply down to better diagnosis, with a 'Hidden Horde' that were never diagnosed in the past, no. Is it genetic; only insofar as, like most things, some genes predispose to Autism when combined with environmental factors. Is it caused by the MMR vaccine or Thimerosal used to preserve vaccines; probably, but only in a small sub-group. His main conclusion is that autism is a collection of symptoms that probably arise from many different causes, but that abnormalities in the immune system, found in many cases but often ignored, are at the root of many cases and affect can many different organs, including the brain. Thus the immune system may be damaged by mercury, by the combined challenge of vaccines like MMR, or by vaccines administered too close together. The damage may arise because of the failure of the body to excrete toxins such as mercury, or because of an inadequate supply of precursors needed in the detoxification processes. As would be expected of a condition involving the immune system, families and offspring of autistics tend to suffer a higher proportion of auto-immune diseases like allergies, asthma, and rheumatism than the general population.

All pretty convincing, and well supported by the evidence presented. I have always thought that Andrew Wakefield's ideas were unfairly dismissed, and that claims that 'large scale meta-studies disprove his theory that MMR vaccine is the cause' were a lie. Wakefield never claimed MMR as the cause of all autism, but was concerned with a sub-set of patients with bowel disorders. Meta-studies, because they include all variants of autism, in widely varying populations, would of course be expected to dilute any effect of MMR vaccine, or any other cause specific to a sub-group, probably to negligible proportions. This does not constitute 'disproof', and Wakefield himself has never gone back on his claims. Allegations that Wakefield's work 'has been discredited', say little about the work itself and are based on the fact that he himself was found guilty of malpractice because he took blood from children without permission - ethically wrong, but nothing to do with the research itself.

I would give the book five stars for it's content, but have downgraded because of his statement that autism is 'not a psychological disorder'. Of course it is, as is anything that affects brain and behaviour, and as such it is a valid subject for study by psychologists. The Author's treatment of Bruno Bettleheim (who did not use the term 'refrigerator mother' but is forever condemned by it) is not as fair as his treatment of Wakefield. My reading of Bettleheim's work leaves me thinking that he was a genuine and caring worker; though some reports of his treatment regime leave me worried. The authors' comment that his theory was 'insulting' are a let-down in an otherwise scientific work. Science must never be put off because a hypothesis is 'insulting' or 'distressing', and my own view is that a sub-set of autistic children are the result of failure of the complex series of interactions between carers (not necessarily mother) and child which are necessary to proper development of the psyche. Psychodynamics is far from dead, having been moved on from Freud's wild assertions through the work of John Bowlby and others in the field of Attachment theory. Studies in the UK of Romanian orphans, deprived of proper interactions with adults at an early stage, show that many of them have characteristics of autism. 'Doctoring the Mind' by Richard Bentall (University Professor and clinical psychologist), and 'The Cradle of Thought' by Peter Hobson (Professor of Developmental Psychopathology), are good books to read for up to date views on this side of the story. The mind does surely need certain minimal levels of proper early interaction in order to develop properly, and we must surely not leave out poor interaction as a possible cause of autism (and many other mental conditions) in a subset of cases, probably linked of course to a genetic predisposition that makes the process more vulnerable to failure. Sadly, this book dismisses psychodynamic processes quite unfairly, without any of the rigour given to other factors. The authors say of Bettleheim, 'he was not even an MD'. Many might equally say of the authors, 'they are not even psychologists'!

There's another aspect of Autism that fails to get a mention in this book, and that is its predominance in males, in whom it also merges with the normal spectrum. The obsession with mechanisms, and with collecting that is so often seen in boys as young as one year old, seems to have relevance to the autism spectrum, and especially to Asperger's syndrome. This trait is perhaps seen especially in the British, and is possibly linked to the emergence of the industrial revolution in Britain, and the predominant role played by Englishmen in the Scientific Enlightenment. Train-spotters, stamp collectors, boffins and model railway enthusiasts are common archetypes, especially of Britain in the 1950s and 60's but have perhaps become less visible in recent times. Fred Dibnah, the steeplejack and steam engine enthusiast who became famous through his television series, was for me the archetypal ingenious and obsessional, yet highly valuable, englishman bordering on Aspergers. Linked to this is the Aspergers versus 'Neurotypical' debate, with many 'Aspies' doubting the superiority or validity of the neurotypical experience. It's not hard to see that so-called 'social skills' often conflict with reason, so that society has a role to play here in causing stress to those who are particularly good at rational thinking. The 'man of honour' who always tells the truth has a hard time in today's world where huge pressure exists for men to 'embrace their feminine side' and put relationships before truth.

10 people found this helpful

Tarmo

Interesting...

Reviewed in the United Kingdom on April 9, 2009

Verified Purchase

CHANGING THE COURSE OF AUTISM shows that this disease can be treated by reducing the neurological inflammation that is part of the disease process, rather than simply masking the symptoms with drugs like Risperdal and Prozac. The authors have seen autistic behaviors improve dramatically or disappear completely with appropriate medical treatment.

3 people found this helpful

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